Kleo follows the U.S. health guidelines for screening recommendations in Kleo for two main reasons: 1.⁠ ⁠Clinical rigor and global trust: The U.S. has invested heavily in medical research and public health infrastructure. As a result, their screening guidelines — like those from the U.S. Preventive Services Task Force (USPSTF) — are internationally respected for being evidence-based, regularly updated, and widely referenced. 2.⁠ ⁠Compliance alignment: We’re registering Kleo in the U.S. and aim to meet the more stringent regulatory expectations there. Using U.S. guidelines ensures we’re aligned with global best practices from both a clinical and compliance perspective. While South Africa does have national health protocols, it does not have a publicly accessible, centralized set of preventive screening guidelines that are as detailed, consistently updated, or transparent as those in the U.S. In practice, many South African clinicians reference international frameworks (like the U.S. or WHO) when making screening recommendations, especially in private care.